Viewed: 03:54:33 in December 11, 2019

Bioinspired Metal-Free Formal Decarbonylation of ﾎｱ-Branched Aliphatic Aldehydes at Ambient Temperature (Richter, Sven C.; Oestreich, Martin)
Chem. Eur. J. 2019, 25 (36), 8508−8512.

Keywords: mCPBA; triethylsilane; BF₃·OEt₂; TPFB

アルデヒドの脱カルボニル化反応。金属を使わずできるのがこの論文のウリのようです。

普段から金属触媒を使った反応を扱っていると奇異に思えるかもしれませんが、反応スキーム自体は既存の、教科書的と言っていいくらいよく知られた反応を組み合わせたもので、確かにこういうのもやろうと思えばできるよなあと。酸化反応と還元反応のペアですか。スキームの二段目のところで副反応によるアルケン生成を気にしないといけないといけないかもしれません。

生成物の水素原子はトリエチルシラン由来の物のようですね。アルデヒド由来のものではないことは重水素化したアルデヒドの反応で確かめているようです。あと、Supporting Informationには反応速度の同位体効果の検討も記述されています。

反応の適用範囲を知りたいので、読みたい論文に追加です。アルデヒドのα炭素が不斉中心になっているアルデヒド、最初の酸化反応で高額純度が少し落ちるようです。

 

準結晶の発見
(Dan Shechtman)
東日本大震災による科研費支払い分割
世界化学年
「タイガーマスク運動
Mac App Storeオープン
ニュージーランド地震(M6.3)
世界初の燃料電池発電実証実験
東日本大震災(M9.0)
「TIGER & BUNNY」放送
地上デジタルテレビ放送へ全面移行
「PONPONPON」(きゃりーぱみゅぱみゅ)
「コクリコ坂から」放映
藤子・F・不二雄ミュージアムがオープン
「千本桜」(WhiteFlame feat.初音ミク)
「家政婦のミタ」放送
スティーブ・ジョブズ氏死去
世界人口が70億人に達する
「なでしこジャパン」
「ラブ注入」

 

ここの画像を使用しています。

高知の漁港はリトル水族館でした。

 

Just finished the calculations: aminopropyl)tetramethyldisiloxane https://t.co/ckR4aeozRg pic.twitter.com/rMLAPim3a4

— nanoniele (@nanoniele) July 1, 2019

 

　

 

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